Table 4.

Rankings of the 22 AD-associated genes among the list of 23,995 prioritized genes when the input phenotypes “abnormal microglial cell morphology,” “abnormal microglial cell physiology,” and “microgliosis” were used separately or combined. A mean value of top 10.59% means that on average the 22 AD genes ranked in the top 10.59% among the prioritized list of 22,982 genes, which was significantly higher than the expected ranking of 50% based on random ranking

Input	Mean (top %)	Median (top %)	P-value
Abnormal microglial cell physiology	10.59	5.31	3.41E−11
Abnormal microglial cell morphology	11.30	7.30	1.92E−11
Microgliosis	113.1	9.48	3.39E−10
Combined	11.49	7.81	6.47E−11