Table 3.

Costs of health care use per patient for PCT-guided decision making and standard care (2015€)

	PCT-guided decision making (n = 754)						Standard care (n = 735)
	All countries	The Netherlands	Switzerland	Canada	Czech Republic	P valuea	All countries	The Netherlands	Switzerland	Canada	Czech Republic	P valuea
All patients	3649 [1496, 4091]	2750 [1315, 3304]	5813 [3073, 7415]	4823 [2271, 5062]	2328 [1360, 3160]*	< 0.001*	3616 [1639, 4372]	2710 [1456, 3272]	6091 [3579, 6965]	4844 [2366, 5867]	1242 [780, 1618]*	< 0.001*
Per risk category
Infection possible (medium risk)	4247 [1989, 4833]	3375 [1667, 3726]	6324 [3376, 7957]	4511 [2221, 4850]	2294 [1240, 3337]*	< 0.001*	4238 [2023, 5021]	3260 [1863, 3467]	6474 [3350, 7947]	4867 [2298, 6343]	1279 [812, 1768]*	< 0.001*
Infection unlikely (low risk)	2960 [1295, 3389]*	2255 [1210, 3062]*	3977 [2404, 5346]*	5218 [2277, 5526]	2415 [1730, 3160]*	< 0.001*	2962 [1424, 3591]*	2267 [1316, 3166]*	4958 [3781, 6314]*	4818 [2495, 5046]	1195 [628, 1559]*	< 0.001*
P valuea	< 0.001*	< 0.001*	0.004*	0.864	0.508		< 0.001*	< 0.001*	0.322	0.697	0.456
Per gestational age (GA)
GA < 37 weeks	6436 [2853, 8728]	5609 [2638, 8653]	9760 [6407, 11596]	5466 [2302, 5610]	2978 [1500, 4267]*	< 0.001*	6098 [2881, 7945]	5354 [2779, 7349]	9045 [4858, 11572]	4867 [2648, 6580]	884 [605, 1263]*	< 0.001*
GA ≥ 37 weeks	2928 [1376, 3468]	2234 [1276, 3150]*	4069 [2615, 4794]*	4585 [2173, 4989]	2133 [1174, 2913]*	< 0.001*	2986 [1538, 3494]	2245 [1416, 3141]*	4427 [3253, 5127]*	4836 [2315, 5681]	1304 [812, 1768]*	< 0.001*
P valuea	< 0.001*	< 0.001*	< 0.001*	0.454	0.269		< 0.001*	< 0.001*	< 0.001*	0.524	0.216

Data are expressed as mean + IQR (interquartile range)

Costs are expressed in € corrected for inflation for the year 2015

^*Significant at a 5% level (P < 0.05)

^aP value for comparison between the subgroups (country, risk category or gestational age)

If costs are ended with *, this indicates statistically significant difference between the PCT-guided decision-making group and standard care group