Figure 6.

Parsing heterogeneity in the affective response to pandemic stressors. Principal component analysis (PCA) identified 7 components explaining 82.0% of the variance in symptoms. (A) Heatmap depicting principal component coefficients (“loadings”) for each clinical symptom in the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 scales. (B) Heatmap depicting how individual subject scores for each component varied with age, gender, work-related factors, and pandemic-related stressors. Warm colors denote statistically significant associations (Kruskal-Wallis analysis of variance [ANOVA] χ², false discovery rate corrected for multiple testing). Pt., patient.