Table 2.
Vasoactive drugs and hormonal therapy in brain death donors–proposed regimen
|
Dosage
|
Comments
|
Vasoactive | ||
Norepinephrine (mcg/kg/min) | ≤ 0.2 mcg/kg/min, if higher dosage needed add vasopressin | In potential heart donors, the lowest dosage is preferable |
Vasopressin (U/h) | Up to 2.5 U/h | |
Hormonal replacement therapy | ||
Idrocorticosteroid | 100 mg bolus, 200 mg/24 h infusion | |
T3 | 4 mcg intravenous bolus, followed by infusion of 3 mcg per hour | T3 could be preferred since it is immediately available to tissues |
Desmopressin (DDVAP) | 4 mcg intravenous bolus eventually repeat every 6 to 8 h as needed |
DDVAP: 1-deamino-8-D-arginine vasopressin.