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. 2021 Oct 7;12:756548. doi: 10.3389/fimmu.2021.756548
ATF6 activating transcription factor 6
AMPK adenosine monophosphate activated protein kinase
APC antigen-presenting cell
BiP binding immunoglobulin protein
CCR2 C-C chemokine receptor-2
CCL2 C-C ligand 2
JNK c-Jun N-terminal Kinase
Clec16A C-type lectin domain family 16, member A
CXCL10 C-X-C motif chemokine ligand 10
Ca2+ calcium
GPx glutathione peroxidase
CCL5 CC ligand 5
ChgA chromogranin-A
CRISPR Clustered Regularly Interspaced Short Palindromic Repeat
CXCR3 CXC receptor 3
DLK1 Delta-like 1
LCMV-WE diabetogenic lymphocytic choriomeningitis virus-WE strain
E embryonic day
ER endoplasmic reticulum
FasL Fas ligand
FISH fluorescence in situ hybridization
GDM gestational diabetes mellitus
Glut2 glucose transporter 2
GSIS glucose-stimulated insulin secretion
Gad65 glutamic acid decarboxylase 65
GWAS Genome-Wide Association Study
HLA human leukocyte antigen
HIPs hybrid insulin peptides
H2O2 hydrogen peroxide
iPSC induced pluripotent stem cell
iNOS inducible nitric oxide
IRE1a inositol-requiring enzyme 1 alpha
INS INSULIN
IFNγ interferon gamma
IL-1β interleukin-1 beta
IP-10 IFNγ inducible protein 10
IAPP islet amyloid polypeptide
LADA latent autoimmune diabetes in adults
MHC major histocompatibility chain
MODY maturity onset diabetes of the young
MCP)-1 monotype chemoattractant protein
NOD non-obese diabetic
NFκB nuclear factor κB
Pdx1 pancreatic and duodenal homeobox 1
pLNs pancreatic lymph nodes
PAD peptidyl arginine deiminase
PTM post-translational modification
Pref-1 preadipocyte factor 1
PAK-2 protein activated kinase 2
PERK protein kinase RNA-like endoplasmic reticulum kinase
RANTES regulated on activation, normal T cell expressed and secreted
ROS reactive oxygen species
Rnls renalase
SNPs single nucleotide polymorphisms
SOD superoxide dismutase
T1DGC T1D Genetics Consortium
TUDCA tauroursdoxycholic acid
TRX thioredoxin
TXNIP thioredoxin interacting protein
tTG2 tissue transglutaminase 2
TLR4 Toll like receptor-4
TNFα tumor necrosis factor alpha
T1D Type 1 diabetes
T2D Type 2 diabetes
UPR unfolded protein response
UCN-3 urocortin-3
VNTR variable number tandem repeat
WTCCC Wellcome Trust Case Control Consortium