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. Author manuscript; available in PMC: 2021 Oct 21.
Published in final edited form as: Sci Immunol. 2016 Nov 18;1(5):eaaf8471. doi: 10.1126/sciimmunol.aaf8471

Fig. 3. Tslpr-deficient mice have increased MRSA burden during in vivo skin infection.

Fig. 3

(A–G) Mice were infected with MRSA i.d. in the ear. (A) TSLP protein expression in the ear after i.d. MRSA infection (n=4), naïve controls were mock-infected with PBS only. (B–G) Ears were analyzed on day 1 p.i. (B) Representative TSLPR expression on neutrophils. (C) Analysis of CFU in the ear of WT (n=11) and Tslpr−/− mice (n=12 ears). (D–F) Analysis of neutrophils in the ear. Shown are representative FACS plots (D) and percent (E) and total number (F) of neutrophils from WT and Tslpr−/− mice (n=8 ears). (G) CFU of MRSA in the ear on day 2 post-i.d. ear infection of WT mice treated with human IgG1 Fc isotype control or TSLPR Fc (two-tailed Mann-Whitney test) (n=8 ears). *, p < .05; **, p < .01; ***, p < .001; ns = not significant. a–f, two-tailed Student’s t-test. Data are representative of 3 (or 2 for (G)) independent experiments.