Table 3.

Correlation between histopathological and dermoscopic findings in the various vesiculobullous disorders

Dermoscopic patterns	Histopathological correlation
Yellowish translucent area	Serum
White globules	Spongiotic microvesicles within epidermis
Pink area	Dilated and tortuous blood vessels
Orange-yellow globules	Serum and red blood cells within blister cavity
Grayish area	Necrotic pigmented epithelium over regenerating non-pigmented epithelium
Brown amorphous area	Dried serum, necrotic keratinocytes, and melanin
Perilesional brown zone	Post-inflammatory pigment and hemosiderin at periphery
White lines	Ballooning degeneration of cells and water retention
Brown dots	Necrotic, ballooned, and degenerated cells with melanin retention
Scales	Hyperkeratosis
Blue-gray globules	Dermal melanin
White shiny rosettes	Narrowing of acrosyringeal infundibula or blockage by keratin
Wickham striae	Compact orthokeratosis and dermal fibrosis
Irregular white network	Spongiosis, papillodermal edema
White linear folds	Overlap of superficial epithelium due to flaccidity