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. 2021 Aug 30;17(4):875–880. doi: 10.4103/1673-5374.322476

Table 2.

Comparisons of laboratory data of ALS patients among the three subgroups according to NLR

Laboratory tests Total NLR on admission P-value

< 2 (n = 544) 2–3 (n = 314) > 3 (n = 172)
WBC (×109/L) 5.88±1.75 5.49±1.59 5.98±1.52 6.90±2.15 < 0.001
Neutrophils (×109/L) 3.57±1.42 2.92±0.97 3.83±1.03 5.10±1.82 < 0.001
Neutrophils (%) 59.66±9.32 52.89±5.76 63.92±3.12 73.33±5.63 < 0.001
Lymphocytes (×109/L) 1.75±0.62 2.02±0.63 1.59±0.41 1.21±0.40 < 0.001
Lymphocytes (%) 30.58±8.40 36.83±5.16 26.70±2.28 17.91±4.08 < 0.001
Monocytes (×109/L) 0.37±0.14 0.36±0.13 0.37±0.13 0.41±0.16 < 0.001
Monocytes (%) 6.42±1.75 6.61±1.72 6.27±1.73 6.10±1.79 0.001
NLR 2.26±1.33 1.48±0.31 2.41±0.28 4.45±1.82 < 0.001
NMR 10.25±4.69 8.61±2.77 11.06±3.40 13.93±7.96 < 0.001
Eosinophils (×109/L) 0.16±0.19 0.17±0.22 0.16±0.14 0.14±0.16 0.229
Basophils (×109/L) 0.03±0.02 0.03±0.02 0.02±0.02 0.02±0.02 0.029
RBC (×1012/L) 4.59±0.54 4.58±0.55 4.63±0.53 4.55±0.49 0.187
Platelet (×109/L) 180.02±61.85 181.01±63.36 180.15±60.01 176.66±60.55 0.723
Hemoglobin (g/L) 137.79±15.92 136.76±15.67 139.54±16.62 137.90±15.19 0.047
HCT 0.42±0.04 0.42±0.04 0.42±0.05 0.42±0.04 0.062
MCV (fL) 91.77±6.19 91.50±6.50 91.73±5.74 92.69±5.88 0.088
MCH (pg) 30.14±2.37 30.02±2.46 30.19±2.20 30.41±2.38 0.147
RDW (%) 13.74±1.15 13.75±1.16 13.69±1.02 13.77±1.34 0.654
HbA1c (%) 5.70±0.72 5.71±0.67 5.75±0.83 5.62±0.63 0.158
Albumin (g/L) 42.40±3.73 42.39±3.78 42.34±3.71 42.51±3.63 0.891

Data are presented as the mean ± SD and were analyzed by one-way analysis of variance. ALS: Amyotrophic lateral sclerosis; HbA1c: hemoglobin A1c; HCT: hematocrit; MCH: mean corpuscular hemoglobin; MCV: mean corpuscular volume; NLR: neutrophil-to-lymphocyte ratio; NMR: neutrophil-to-monocyte ratio; RBC: red blood cell; RDW: red blood cell distribution; WBC: white blood cell. From the Department of Laboratory Medicine in the West China Hospital of Sichuan University, the reference ranges are 40–75% for neutrophils, 20–50% for lymphocytes, and 3–10% for monocytes in healthy controls.