Additional Table 1.

Results of the rotation of Parkinson’s disease model rats

Group	Rotations (times/min)
6-OHDA	9.11±0.92
5-BDBD+6-OHDA	9.16±0.99
P2X4R-NC+6-OHDA	9.21±1.06
P2X4R-RNA+6-OHDA	9.47±1.28
P2X4R-siRNA+ 6-OHDA	9.26±0.99

Data are expressed as mean ± SEM (n = 20 mice/group). Control group: After 1 week of pretreatment with 0.9% physiological saline, ascorbic acid was injected into the SNpc stereotactically; 5-BDBD + 6-OHDA group: after 1 week of pretreatment with 5-BDBD, 6-OHDA was injected into the SNpc stereotactically; P2X4R-NC + 6-OHDA group: after 1 week of pretreatment with the negative control lentivirus, 6-OHDA was injected into the SNpc stereotactically; P2X4R-RNA + 6-OHDA group: after 1 week of pretreatment with the lentivirus carrying P2X4R, 6-OHDA was injected into the SNpc stereotactically; P2X4R-siRNA + 6-OHDA group: after 1 week of pretreatment with the lentivirus carrying siRNA targeting P2X4R, 6-OHDA was injected into the SNpc stereotactically. 5-BDBD: 5-(3-Bromophenyl)-1,3-dihydro-2H-benzofuro[3,2-e]-1,4-diazepin-2-one; 6-OHDA: 6-hydroxydopamine; NC: negative control lentivirus; P2X4R: P2X4 receptor; siRNA: small-interfering RNA; SNpc: substantia nigra pars compacta.