Fig. 1.
Autoimmune liver disease in a 7-year-old boy. a, b Coronal single-shot fast spin-echo (a) and axial T2-weighted fast spin-echo fat-saturated (b) MR images show areas of geographic liver signal hyperintensity, marked splenomegaly (with an area of splenic infarction) and ascites. c, d MR elastography images of the liver (c) and spleen (d) show abnormally increased stiffness (4.8 kPa and 7.4 kPa, respectively). Note that the splenic region-of-interest was drawn to avoid the area of splenic infarction. e, f Iron-corrected T1 (cT1) (e) and T2 (f) maps show heterogeneous appearance of the liver with areas of focally increased T1 (mean=1,003.4 ms) and T2 (mean=66.0 ms) values, particularly in the right lobe. The T2 map shows mild motion artifacts. g Diffusion-weighted imaging apparent diffusion coefficient (ADC) map shows that the liver is diffusely hypointense, with lower than expected mean ADC value (0.93×10−3 mm2/s)
