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. 2021 Oct 7;13:669490. doi: 10.3389/fnagi.2021.669490

TABLE 2.

Characteristics of cognitively normal participants by subgroup.

Study groups
Effect size1
Healthy controls Subjective complaints/No impairments
Number 104 17
Age 65.3 (8.2) 68.6 (6.9) 0.02
Education 16.2 (2.9) 16.4 (4.7) 0.001
Sex [Percent (N) Male] 26.9 (28) 52.9 (9) 0.20*
Race [Percent (N) Caucasian] 56.7 (59) 76.5 (13) 0.15
Handedness [Percent(N) Right] 96.1 (99) 92.9 (13) 0.05
APOE*4 Present [Percent(N)] 27.2 (25) 30.8 (4) 0.01
Montreal Cognitive Assessment 26.4 (2.4) 26.9 (1.4) 0.008
Wide Range Achievement Test – 4 64.1 (5.0) 57.5 (2.1) 0.095
Walk Endurance – 2min distance 523.0 (82.7) 677.5 (419.0) 0.10*
Gait Speed – 4meter walktime 3.4 (0.5) 3.3 (0.4) 0.003
Oral Reading Recognition 6.9 (3.8) 6.7 (2.4) 0.000
Dimensional Change Card Sort Test 29.4 (0.8) 28.7 (1.4) 0.07*
Flanker Inhibitory Control 19.9 (0.8) 20.0 (0.0) 0.002
Pattern Comparison 41.7 (6.1) 41.4 (7.6) 0.000
Picture Sequence Memory 11.8 (6.8) 11.2 (6.9) 0.001
Crystalized Cognition 113.3 (9.6) 114.4 (7.8) 0.002
Fluid Cognition 97.6 (8.9) 97.0 (9.9) 0.001
Total Cognition 105.8 (8.8) 106.0 (9.0) 0.000
Promis Abilities 31.5 (7.0) 27.3 (7.5) 0.04*
Promis Concerns 15.4 (7.0) 20.4 (8.1) 0.06*
General Life Satisfaction 20.0 (7.8) 19.1 (4.5) 0.002
Meaning and Purpose 30.4 (15.9) 21.9 (8.5) 0.04*
Positive Affect 19.3 (13.3) 15.8 (11.7) 0.009
Sadness 8.8 (2.4) 9.0 (2.5) 0.001
Self-Efficacy 20.0 (9.5) 17.2 (8.6) 0.011

1Cramer’s V or Cohen’s f2 p < 0.05.