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. 2021 Oct 21;16(10):e0258942. doi: 10.1371/journal.pone.0258942

Table 1. Mouse models and diet.

Mice Surgery Age* Diet** Surgery
BKS-db/db 6w Chow RYGB or Sham-PF***
NZO 6w HFD RYGB or Sham-PF
STZ 10w Chow RYGB or Sham-PF
B6-db/db 6w Chow RYGB or Sham-PF

*: BKS-db/db, B6-db/db and NZO mice underwent RYGB or sham surgery at 6 weeks of age, and streptozotocin (STZ)-induced diabetic mice underwent RYGB or sham surgery at 10 weeks of age.

**: BKS-db/db, B6-db/db and STZ mice were fed with chow for whole study period. NZO mice were fed with chow up to 6 weeks of age and underwent RYGB or sham surgery followed by high-fat diet (HFD, 60% fat, Bio-Serv) feeding up to the endpoint.

***: Sham-PF, mice undergo sham surgery with pair feeding. The amount of diet provided to the mouse with sham surgery is matched to that consumed by the mouse with RYGB.