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NAC+EE after an additional early-life oxidative challenge recover PV/PNN and MMP9 in Gclm KO at adulthood. (A) Protocol scheme. (B) PV, WFA and MMP9 in Gclm KO and WT mice: confocal images (scale bar: 50 μm) and quantification graphs. Data expressed as mean±s.e.d. (mice N = 5–8). ANOVA analysis: G = genotype, T = treatment, R = recovery, x = interaction; *P < .05; **P < .01; ***P < .001, analyzed by Tukey post-hoc test.
