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. 2021 Oct 20;28(1):2278–2288. doi: 10.1080/10717544.2021.1992037

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — (A) Maximum force of detachment (F_max) expressed in millinewtons (mN) and (B) work of mucoadhesion (W_ad) expressed in microjoules (µJ) of microparticles MB1–MB2 and placebo formulation. Values are expressed as mean ± S.D., n = 5; *significant differences with p ≤ .05, ** with p ≤ .01 and *** with p ≤ .001 in comparison to control-1 (cellulose paper); ^†,††significant differences with p ≤ .05 and p ≤ .01 in comparison to control-2 – commercially available mucoadhesive vaginal product, respectively.