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. 2021 Jul 23;13(7):513–526. doi: 10.1093/jmcb/mjab048

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© The Author(s) (2021). Published by Oxford University Press on behalf of Journal of Molecular Cell Biology, CEMCS, CAS.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Structure of MT1-MMP. (A) Sequence alignment in CLUSTAL format. The alignment was performed using Multiple Alignment using Fast Fourier Transform (MAFFT)FFT-NS-I (v7.429). MT1-MMP: NP_004986; MT2-MMP: NP_002419.1; MT3-MMP: NP_005932; MT5-MMP: NP_006681. (B) Phylogenetic Tree of MT1-MMP, MT2-MMP, MT3-MMP, and MT5-MMP. Branch length is shown in the cladogram. Numbers next to each MT-MMP indicate the actual branch length. (C) A schematic of MT1-MMP. Protein functional motifs are indicated in different colors. TM, transmembrane domain.