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. 2021 May 5;152:233–242. doi: 10.1016/j.ejca.2021.04.019

Table 1.

QALY and productivity losses associated with additional excess cancer deaths by cancer site.

Cancer site Approach Pre-pandemic (observed) First wave pandemic (estimated with 95% CI) Differences in observed and estimated QALY and productivity losses due to additional excess cancer deaths
Breast Deaths 3564 3908 (3891–3926) 344 (326–361)
QALYs (thousands) 37.1 41.3 (40.1–41.6) 4.1 (3.9–4.4)
Productivity losses (GBP million)
 Human capital approach 267.0 290.2 (285.2–295.6) 23.2 (18.2–28.6)
Colorectal Deaths 9416 11,062 (10,982–11,145) 1646 (1566–1729)
QALYs (thousands) 80.9 95.9 (95.0–96.8) 15.0 (14.1–16.0)
Productivity losses (GBP million)
 Human capital approach 410.1 445.8 (432.6–458.8) 35.7 (22.4–48.7)
Lung Deaths 25,800 27,090 (27,081–27,099) 1290 (1281–1299)
QALYs (thousands) 220.1 231.0 (230.1–231.8) 10.9 (9.9–11.7)
Productivity losses (GBP million)
 Human capital approach 805.3 843.6 (819.3–865.2) 38.3 (14.0–59.9)
Oesophagus Deaths 5713 6048 (6038–6047) 335 (325–345)
QALYs (thousands) 50.5 53.2 (52.8–53.7) 2.7 (2.3–3.1)
Productivity losses (GBP million)
 Human capital approach 195.5 202.1 (191.4–213.1) 6.6 (−4.0–17.6)
Total cancer Deaths 44,493 48,109 (48,020–48,200) 3615 (3526–3706)
QALYs (thousands) 388.7 421.4 (419.9–422.8) 32.7 (31.3–34.1)
Productivity losses (GBP million)
 Human capital approach 1677.9 1781.7 (1751.1–-1810.1) 103.8 (73.2–132.2)

Abbreviations: QALY – quality-adjusted life-years discounted to 2019 value.

Notes: 95% confidence intervals obtained from 500 bootstraps, percentile method. Totals may not add up due to rounding.