Table 3.

Comparison of an intercept-only mixed-effects model with models containing random effects to determine the best-fitting model to account for how gestational changes in glycated hemoglobin A_1c (HbA_1c) influence the time in range–HbA_1c relationship

Model	Fixed effects	β	95% CI	P	F	P of the equation
1	Intercept	131.00	(118.56 to 143.44)	.001	77.15	.001
	HbA1c	–8.93	(–10.94 to –6.93)	.001
2	Intercept	125.74	(110.71 to 140.77)	.001	39.41	.001
	HbA1c, %	–8.57	(–0.93 to 0.04)	.001
	Trimesters	1.53	(–0.93 to 3.99)	.222
3	Intercept	125.42	(110.24 to 140.59)	.001	39.47	.001
	HbA1c, %	–8.52	–10.62 to –6.42)	.001
	Gestation, wk	0.13	(–0.07 to 0.34)	.208
4	Intercept	96.21	(68.43 to 123.99)	.001	20.34	.001
	HbA 1c , %	–8.46	(–11.44 to –5.49)	.001
	Hb, g/L	0.27	(0.09 to 0.44)	.001
5	Intercept	132.75	(111.76 to 153.74)	.001	26.65	.001
	HbA1c, %	–8.82	(–11.00 to –6.63)	.001
	Gestation, wk	0.47	(–1.68 to 0.74)	.443
	Gestation, wk2	0.01	(–0.01 to 0.04)	.320
6	Intercept	90.51	(50.90 to 130.13)	.001	10.62	.001
	HbA1c, %	–8.02	(–11.39 to –4.64)	.001
	Hb, g/L	0.27	(0.10 to 0.44)	.003
	Gestation, wk	–0.01	(–1.68 to 1.66)	.991
	Gestation, wk2	0.01	(–0.03 to 0.04)	.822

The values in bold shows the best fitting model of TIR-HbA1c relationship.