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. 2021 Jul 17;106(11):3168–3183. doi: 10.1210/clinem/dgab524

Table 1.

Study population characteristics

Patient characteristics (n = 39)
Demographics
Age at surgery (years) – median (IQR) 65 (55, 72)
Sex
 Female 35 (90%)
 Male 4 (10%)
Race
 White 33 (85%)
 Black or African American 0
 Other/Unknown 6 (15%)
Ethnicity
 Hispanic or Latino 3 (8%)
 Non-Hispanic or Latino 36 (92%)
Clinical presentation
 Nephrolithiasis 8 (21%)
 Osteoporosis 7 (18%)
 Osteopenia 18 (46%)
 Number of glands removed
  1 33 (85%)
  2 5 (13%)
  3 1 (2%)
  4 0
Preoperative biochemistry Median (IQR)
 Intact PTH (pg/ml) 104 (85, 133)
 Serum calcium (mg/dL) 10.8 (10.4, 11.0)
 Serum creatinine (mg/dL) 0.76 (0.68, 0.99)
 Vitamin 25 D (ng/mL) 33.65 (28.25, 42.75)
Preoperative bone density Median (IQR)
 Lowest T-score −1.95 (−2.78, −1.03)

Parathyroid adenomas were obtained under an IRB-approved protocol with fully informed consent from a sequential series of 39 patients undergoing surgery for primary hyperparathyroidism at our institution. All study participants were nonfamilial, sporadic PHPT patients. Race and ethnicity were self-reported by the study participants. The presence of nephrolithiasis, osteoporosis, or osteopenia was noted from the patients’ preoperative medical record and referral history. Preoperative biochemical values were determined from blood drawn at the patient’s clinic appointment prior to scheduling surgery. T-scores were determined from the patient’s referral medical records.

Abbreviations: IQR, interquartile range; PTH, parathyroid hormone.