Table 1.
Study population characteristics
| Patient characteristics | (n = 39) |
|---|---|
| Demographics | |
| Age at surgery (years) – median (IQR) | 65 (55, 72) |
| Sex | |
| Female | 35 (90%) |
| Male | 4 (10%) |
| Race | |
| White | 33 (85%) |
| Black or African American | 0 |
| Other/Unknown | 6 (15%) |
| Ethnicity | |
| Hispanic or Latino | 3 (8%) |
| Non-Hispanic or Latino | 36 (92%) |
| Clinical presentation | |
| Nephrolithiasis | 8 (21%) |
| Osteoporosis | 7 (18%) |
| Osteopenia | 18 (46%) |
| Number of glands removed | |
| 1 | 33 (85%) |
| 2 | 5 (13%) |
| 3 | 1 (2%) |
| 4 | 0 |
| Preoperative biochemistry | Median (IQR) |
| Intact PTH (pg/ml) | 104 (85, 133) |
| Serum calcium (mg/dL) | 10.8 (10.4, 11.0) |
| Serum creatinine (mg/dL) | 0.76 (0.68, 0.99) |
| Vitamin 25 D (ng/mL) | 33.65 (28.25, 42.75) |
| Preoperative bone density | Median (IQR) |
| Lowest T-score | −1.95 (−2.78, −1.03) |
Parathyroid adenomas were obtained under an IRB-approved protocol with fully informed consent from a sequential series of 39 patients undergoing surgery for primary hyperparathyroidism at our institution. All study participants were nonfamilial, sporadic PHPT patients. Race and ethnicity were self-reported by the study participants. The presence of nephrolithiasis, osteoporosis, or osteopenia was noted from the patients’ preoperative medical record and referral history. Preoperative biochemical values were determined from blood drawn at the patient’s clinic appointment prior to scheduling surgery. T-scores were determined from the patient’s referral medical records.
Abbreviations: IQR, interquartile range; PTH, parathyroid hormone.