Table 3.
Results of MR analyses
| Males (1-sample MR: UKB) | Males (2-sample MR:UKB-GEFOS) | Females (1-sample MR: UKB) | Females (2-sample MR:UKB-GEFOS) | |||||
|---|---|---|---|---|---|---|---|---|
| MR method | Estimate | P-value | Estimate | P-value | Estimate | P-value | Estimate | P-value |
| GSMR | 9.89E-02 | 1.57E-11 | 1.82E-01 | 2.08E-04 | 3.27E-02 | 7.48E-06 | 3.69E-01 | 1.67E-03 |
| Weighted median | 6.61E-02 | 2.82E-02 | 2.65E-01 | 7.44E-05 | 7.31E-02 | 1.26E-01 | 4.19E-01 | 3.54E-03 |
| IVW | 1.48E-01 | 5.49E-05 | 1.82E-01 | 3.47E-03 | 1.45E-01 | 9.98E-02 | 2.45E-01 | 2.57E-01 |
| MR-Egger | 1.42E-01 | 2.23E-01 | 4.50E-01 | 2.73E-02 | 4.81E-01 | 2.56E-02 | 3.96E-01 | 7.92E-01 |
| MR-Egger intercept | 8.87E-04 | 6.95E-01 | −4.01E-02 | 1.07E-01 | −3.63E-02 | 1.71E-01 | −1.29E-02 | 9.15E-01 |