Table 4.
Sample (sex) | STR source (passage or generation) | AM | CSF1PO | D5S818 | D7S820 | D13S317 | D16S539 | TH01 | TPOX | vWA | Identitya (%) |
---|---|---|---|---|---|---|---|---|---|---|---|
MDA-ATC1 | Frozen tissue | X | 10,12 | 11,14 | 9,12 | 11,12 | 11 | 9.3 | 8 | 16,18 | 100 |
(Female) | MDA-T187 cell line (p28) | X | 12 | 14 | 9,12 | 12 | 11 | 9.3 | 8 | 16,18 | 88.5 |
PDX (F1) | X | 10,12 | 11,14 | 12 | 12 | 11 | 9.3 | 8 | 16,18 | 92.3 | |
MDA-ATC2 | Frozen tissue | X,Y | 12,13 | 9,12 | 10,12 | 11,12 | 11,12 | 6,9.3 | 8,12 | 17,18 | 100 |
(Male) | PDX (F3) | X,Y | 12,13 | 9,12 | 10,12 | 12 | 11 | 6,9.3 | 8,12 | 17,18 | 92.3 |
MDA-ATC3 | Frozen tissue | X | 10,12 | 12 | 9,12 | 11,12 | 8,10 | 6,9.3 | 8,12 | 14,15 | 100 |
(Female) | PDX (F3) | X | 12 | 12 | 12 | 11 | 8,10 | 6,9.3 | 12 | 14 | 73.1 |
MDA-ATC4 | Frozen tissue | X | 12 | 9,11 | 11 | 11,12 | 11,13 | 6,8 | 9,10 | 14,18 | 100 |
(Female) | MDA-T248 cell line (p25) | X | 12 | 9,11 | 11 | 11 | 11,13 | 6,8 | 9,10 | 14,18 | 96.2 |
PDX (F2) | X | 12 | 9,11 | 11 | 11 | 11,13 | 6,8 | 9,10 | 14,18 | 96.2 | |
MDA-ATC5 | Frozen tissue | X,Y | 11,14 | 12 | 8,10 | 11,12 | 11,13 | 6 | 8,11 | 14,17 | 100 |
(Male) | MDA-T269 cell line (p20) | X | 11,14 | 12 | 10 | 11,12 | 11,13 | 6 | 8,11 | 14,17 | 96.2 |
PDX (F3) | X | 11,14 | 12 | 10 | 11,12 | 11,13 | 6 | 8,11 | 14,17 | 96.2 | |
MDA-ATC6 | Frozen tissue | X | 11,12 | 12 | 10,11 | 9,11 | 11 | 7,9 | 8,11 | 14,17 | 100 |
(Female) | MDA-T273 cell line (p21) | X | 11,12 | 12 | 10,11 | 9 | 11 | 7,9 | 8,11 | 14 | 92.3 |
PDX (F3) | X | 11,12 | 12 | 10,11 | 9 | 11 | 7,9 | 8,11 | 14 | 92.3 |
Abbreviations: PDX, patient-derived xenograft; STR, short-tandem repeat.
a Percentage identity was determined by Tanabe algorithm based on 13 loci. Percentage match = (number shared loci × 2)/(total number of loci in the questioned profile + total number of loci in the reference profile). Reference profile was frozen tissue.