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Average change between 1-min steady-state values taken during exercise (3.2 km/h, 0% grade) and during exercise with muscle metaboreflex activation before (gray) and after administration of intrathecal RTX (2 µg/kg) (L4–L6) (red). Standard error shown on bar graphs with actual data points overlain. †Statistical significance (P < 0.05, Student’s paired t test) compared with previous condition (n = 6 animals). RTX, resiniferatoxin.
