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. 2021 Oct 22;297(5):101329. doi: 10.1016/j.jbc.2021.101329

Table 2.

List of known SARS-CoV-2 epitopes identified to be produced by the enzymatic digestion of the S1 glycoprotein peptide pool

Sequence Produced by ERAP1 allotype
Possible MHC restriction Reference
1 2 3 4 5 6 7 8 9 10
ALNTLVKQL graphic file with name fx1.gif HLA-A∗02:01 (37)
QPYRVVVLSF HLA-B∗07:02 (7)
RLDKVEAEV HLA-A∗02:01 (9)
GTHWFVTQR HLA-A∗11:01 (38)
NQKLIANQF HLA-B∗15:01 (39)
TPINLVRDL HLA-B∗07:02 (9)
IIAYTMSL H2-Kb (40)
NESLIDLQEL HLA-B∗40:01 (7)
IANQFNSAI HLA-B∗51:01 (7)
LGAENSVAY HLA-B∗35:01 (7)
NATRFASVY HLA-B∗35:01 (7)
NITRFQTL HLA-B∗08:01 (7)
NVYADSFVIR HLA-A∗68:01 (7)
RLQSLQTY HLA-B∗15:01 (7)
TLADAGFIK HLA-A∗03:01 (7)
VYYPDKVF HLA-A∗24:02 (7)
SWMESEFRV HLA-A∗24:02 (9)
VLTESNKKF HLA-B∗15:01 (9)
KPFERDISTEIY HLA-B∗40:01 (41)
EVFNATRFASVY HLA-A∗26:01 (7)

The ability of each ERAP1 allotype to produce each of the epitopes is indicated by a grayed box.