TABLE 3.
Comparison of results obtained by line probe assay and sequencing
| Line probe profile | No. of isolates | Mutation(s) identified by sequencinga |
|---|---|---|
| ΔS1 | 6 | 511 cCg (1), 513 cCa (5) |
| ΔS2 | 1 | 516 Tac (1) |
| ΔS3 | 1 | 522 tTg (1) |
| ΔS4 | 3 | 526 cGc (3) |
| ΔS5 | 2 | 531 tGg (2) |
| R2 | 12 | 516 gTc (12) (Asp→Val) |
| R4a | 8 | 526 Tac (8) (His→Tyr) |
| R4b | 4 | 526 Gac (4) (His→Asp) |
| R5 | 46 | 531 tTg (46) (Ser→Leu) |
| WT/R2b | 1 | None |
| WT | 6 | 514 TTC ins.c (2), none (4) |
a
Capital letters in the codon indicate the change in nucleotide sequence. Values in parentheses are number of isolates.
b
Mixed culture (a wild-type [WT] plus an R2 strain).
c
ins., insertion.