| Study characteristics |
| Methods |
C: sealed envelopes (? opaque and sequentially numbered)
DVT assessment blinded
Ex during trial: none
Losses to FU: none |
| Participants |
UK
32 participants
Mean age: 78 years
34% male
No CT, 100% LP before entry
Any stroke with no blood in CSF
Less than 48 hours since stroke onset |
| Interventions |
Rx: heparin 5000 IU subcutaneous 8‐hourly
Control: no treatment
Duration: 14 days |
| Outcomes |
Death but not cause of death
DVT (systematic I‐125 scan) |
| Notes |
Ex: BP > 120 diastolic, bleeding risk
FU: 1 month |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Methods used for random sequence generation not described |
| Allocation concealment (selection bias) |
Unclear risk |
No clear description provided, reported only "randomly" assigned |
| Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
No information given |
| Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
Personnel not blinded to treatment |
| Blinding of outcome assessment (detection bias)
All outcomes |
Low risk |
Results done by a blinded second doctor who did not know the patients |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
No detailed number of patients who completed follow‐up reported |
| Selective reporting (reporting bias) |
Low risk |
Mentioned outcomes reported |
