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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: J Neurochem. 2021 Aug 17;159(2):273–291. doi: 10.1111/jnc.15463

Figure 3. IPA identified upstream regulators and causal networks.

Figure 3.

A. Heat map depicting the differentially expressed proteins (≥ 50% increase or ≥ 34% decrease, p < 0.05) in the cortex, hippocampus and thalamus of rTg-DI rats associated with upstream regulator TNFα. B. Heat map depicting differentially expressed proteins in the cortex, hippocampus and thalamus of rTg-DI rats associated with upstream regulator TGFβ1. C. Heat map depicting the differentially expressed proteins in the cortex, hippocampus, and thalamus of rTg-DI rats associated with the F2/Thrombin causal network. Red indicates increased, green decreased and grey not differentially expressed proteins, and color intensity correlates with degree of change.