Table 1.

Factors associated with BPD-PH which may contribute to the development of BPD-PH in the child born prematurely.

Prenatal Factors	Postnatal Factors
Maternal hypertensive vascular disease of pregnancy	Toxicity from prolonged hyperoxic exposure
Anomalies of the placenta	Toxicity from prolonged hypoxemic exposure
Intrauterine growth restriction and associated conditions (e.g., oligohydramnios and small for gestational age)	Physical trauma from mechanical ventilation and related support
Chorioamnionitis or other infections	Sepsis or other infections
Fetal and/or maternal epigenic changes	Hemodynamic alterations related to patent ductus arteriosus (PDA) or congenital heart disease
	Retinopathy of prematurity (ROP)
	Necrotizing enterocolitis (NEC)
	Stenosis of one or more pulmonary veins