TABLE 3.
Baseline characteristics of patients with CRE infection.
| Variables | CPE (n = 69) | Non-CPE (n = 59) | p value |
|---|---|---|---|
| Age, years | 64(53–78) | 62(54–74.5) | 0.833 |
| Sex | 0.873 | ||
| Male | 50(72.5%) | 42(71.2%) | |
| Female | 19(27.5%) | 17(28.8%) | |
| aCCI | 4(2–6) | 4(2.5–7) | 0.466 |
| Pitt bacteraemia score | 2(0–2) | 1(0–2) | 0.357 |
| Time to positive culture, days | 9(2.5–21) | 9(2–21) | 0.770 |
| Community onset | 21(30.4%) | 19(32.2%) | 0.830 |
| Admitted from home | 36(52.2%) | 38(64.4%) | |
| Hospital transfer | 33(47.8%) | 21(35.6%) | 0.162 |
| ICU admission | 34(49.3%) | 16(27.1%) | 0.01 |
| The length of ICU stay, days | 22(8.5–31.5) | 10.5(5.25–26) | 0.045 |
| Antimicrobial exposure | 60(87.0%) | 52(88.1%) | 0.841 |
| Surgery | 30(43.5%) | 32(54.2%) | 0.225 |
| Transplant history | 2(2.9%) | 3(5.1%) | 0.525 |
| Multiple organ dysfunction | 19(27.5%) | 9(15.3%) | 0.198 |
| History of blood transfusion | 28(40.6%) | 18(30.5%) | 0.296 |
| Chemotherapy | 5(7.2%) | 6(10.2%) | 0.556 |
| Radiotherapy | 0(0.0%) | 1(1.7%) | 0.272 |
| Tumor | 24(34.8%) | 23(39.0%) | 0.623 |
| Infection | |||
| Blood infection | 11(15.9%) | 5(8.5%) | 0.203 |
| Urine infection | 16(23.2%) | 18(30.5%) | 0.350 |
| Respiratory infection | 27(39.1%) | 13(22.0%) | 0.038 |
| Wound infection | 4(5.8%) | 7(11.9%) | 0.222 |
| Intra-abdominal infection | 0(0.0%) | 2(3.4%) | 0.187 |
| Catheter-related infection | 0(0.0%) | 4(6.8%) | 0.028 |
| Other infections | 9(13.0%) | 12(20.3%) | 0.267 |
| Septic shock | 22(31.9%) | 11(18.6%) | 0.088 |
| Intrusive procedure | |||
| Drainage tube | 38(55.1%) | 44(74.6%) | 0.022 |
| Urinary catheter | 44(63.8%) | 48(81.4%) | 0.027 |
| Venous catheterization | 41(59.4%) | 36(61.0%) | 0.854 |
| Arterial catheterization | 28(40.6%) | 21(35.6%) | 0.563 |
| Mechanical Ventilation | 33(47.8%) | 25(42.4%) | 0.537 |
| Tracheal intubation | 28(40.6%) | 21(35.6%) | 0.563 |
| Tracheotomy | 18(26.1%) | 8(13.6%) | 0.079 |
| Bronchoscope | 12(17.4%) | 11(18.6%) | 0.54 |
| Underlying disease | |||
| Respiratory system diseases | 45(65.2%) | 29(49.2%) | 0.067 |
| Urinary system diseases | 22(31.9%) | 22(37.3%) | 0.521 |
| Cardiovascular diseases | 40(58.0%) | 31(52.5%) | 0.538 |
| Cerebrovascular disease | 19(27.5%) | 18(30.5%) | 0.712 |
| Immune system diseases | 5(7.2%) | 2 (3.4%) | 0.339 |
| Blood system diseases | 26(37.7%) | 16(27.1%) | 0.205 |
| Central nervous system disease | 11(15.9%) | 9(15.3%) | 0.915 |
| Endocrine system diseases | 9(13.0%) | 10(16.9%) | 0.536 |
| Hepatobiliary system disease | 42(60.9%) | 25(42.4%) | 0.037 |
| Gastrointestinal disease | 24(34.8%) | 25(42.4%) | 0.379 |
| Urinary system disease | 33(47.8%) | 22(37.3%) | 0.230 |
| Peripheral vascular disease | 14(20.3%) | 11(18.6%) | 0.815 |
Data are expressed as n (%) of patients for categorical variables and median (IQR) for continuous variables as appropriate. p values of ≤0.05 were presented by bold values.