Figure 4.

Box plots and individual plots of neutralizing antibody (nAb) titres over time after two doses of AZD1222 or placebo in Japanese participants (fully vaccinated analysis set), determined by pseudo-virus neutralization assay. The bottom and top edges of the box indicate the first and third quartiles [the difference is the interquartile range (IQR)], the line inside the box is the median, and the diamond mark inside the box is the geometric mean. The whiskers that extend from the box indicate the minimum and maximum within the range of 1.5 × IQR from the box. Box plots are created using log-transformed values. Titre values measured as below the lower limit of quantification (LLoQ) (40) are imputed to a value that is half of the LLoQ. Titre values measured as above the upper limit of quantification (ULoQ) (787,339) are imputed at the ULoQ value.