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. 2021 Oct 21;11:20761. doi: 10.1038/s41598-021-99652-8

Figure 5.

Figure 5

Schematic overview of glycogen metabolism and Cori cycle. (a) Intracellular glycogen synthesis and breakdown including rate-limiting enzymes glycogen synthase (GYS) and glycogen phosphorylase (PYGL). (b) Cori cycle-gluconeogenesis is reverse process of glycolysis with exception for reactions catalyzed by rate-limiting enzymes of gluconeogenesis: PCK, FBPase and G6Pase. G6P-glucose-6-phosphate, G1P-glucose-1-phosphate, UDP-G-UDP-glucose. (c) Cartoon summary of bulbar and suprabulbar anagen HF with localization of glycogen and key proteins of glycogen metabolism and gluconeogenesis in the HF epithelium. Figures (a) and (b) were created using Servier Medical Art templates, which are licensed under a Creative Commons Attribution 3.0 Unported License; https://smart.servier.com.