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. 2021 Oct 21;11:20866. doi: 10.1038/s41598-021-00286-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Ratios of lipids as predictive tests for respiratory distress. Abundance profile of subclasses of ceramides in the plasma of COVID-19 infected patients with mild and respiratory distress symptoms in terms of fold changes in observed peak area, compared to the plasma of uninfected individuals (a), Comparative view of changes in concentration of ceramide subclasses in the plasma of COVID-19-infected mild and with respiratory distress symptoms, from the uninfected, in terms of µmol/l (b), Relative abundance profile of subclasses of ceramides as represented by the ratio of peak areas of Cer/HexCer (c) and Cer/dhCer (Ceramide / dihydroceramide) ratios (d) in the plasma of COVID-19 infected patients with mild vs respiratory distress symptoms. Error bars represent, standard deviation of replicates.

Ratios of lipids as predictive tests for respiratory distress. Abundance profile of subclasses of ceramides in the plasma of COVID-19 infected patients with mild and respiratory distress symptoms in terms of fold changes in observed peak area, compared to the plasma of uninfected individuals (a), Comparative view of changes in concentration of ceramide subclasses in the plasma of COVID-19-infected mild and with respiratory distress symptoms, from the uninfected, in terms of µmol/l (b), Relative abundance profile of subclasses of ceramides as represented by the ratio of peak areas of Cer/HexCer (c) and Cer/dhCer (Ceramide / dihydroceramide) ratios (d) in the plasma of COVID-19 infected patients with mild vs respiratory distress symptoms. Error bars represent, standard deviation of replicates.