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. 2021 Oct 21;11:20766. doi: 10.1038/s41598-021-99960-z

Figure 2.

Figure 2

Morphologic profiling of Sulfasalazine, DHA and the novel hybrid compound AC254 on rodent glioma cells. (A) Rat glioma cells (F98) were treated with a range of concentrations of SAS, DHA, AC254, SAS and solvent DMSO combined with DHA. Cell morphology was examined after 72 h with light microscopy. Olympus × 71 with cell F-Software (Olympus). Scale bar, 200 µM. (B) F98 were treated with 0.5 µM of SAS, DHA, AC254 and SAS combined with. Cells were fixated and stained with actin marker Phalloidin 488 and DNA marker Hoechst after 24 h of treatment. Axio Observer with Zen Software (Zeiss). Scale bar: 20 µm.