Table 2.

Relative organ weights of SD rats treated orally with galacto-oligosaccharide (GOS), assessed in acute and subacute toxicity tests

Relative organ weight (g/100 g of body weight)	Acute toxicity			Subacute toxicity
	Control	GOS		Control	GOS
Female
Liver	3.43±0.21	3.18±0.11		2.92±0.36	3.10±0.24
Kidney	0.77±0.01	0.75±0.03		0.72±0.05	0.70±0.05
Spleen	0.29±0.03	0.28±0.02		0.28±0.06	0.27±0.02
Heart	0.49±0.03	0.44±0.04		0.43±0.04	0.41±0.05
Lung	0.57±0.11	0.60±0.10		0.50±0.06	0.52±0.08
Male
Liver	3.22±0.35	3.31±0.26		3.18±0.32	3.08±0.27
Kidney	0.75±0.08	0.78±0.07		0.76±0.08	0.76±0.05
Spleen	0.26±0.03	0.24±0.02		0.25±0.03	0.24±0.02
Heart	0.41±0.04	0.49±0.05		0.41±0.04	0.46±0.04
Lung	0.61±0.08	0.59±0.09		0.52±0.09	0.51±0.07

Values are mean±SD for 5 rats/group.

The differences between the control and treated groups were evaluated by Student’s t-tests.

Group for acute toxicity was given water vehicle or GOS at 5,000 mg/kg once followed by no treatment for 14 days. Group for subacute toxicity was given water vehicle or GOS at 1,000 mg/kg daily for 28 days.