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. 2021 Oct 8;11:702322. doi: 10.3389/fonc.2021.702322

Table 2.

Risk factors associated with early-onset colorectal neoplasm.

Crude OR (95% CI) Multivariable-adjusted OR a (95% CI)
Male 2.49 (1.72-3.61) 1.94 (1.12-3.36)
BMI 1.09 (1.03-1.15) 1.07 (1.01-1.14)
Family history of colorectal cancer 4.96 (2.95-8.33) 5.17 (3.07-8.72)
Smoking
 Nonsmoker 1 1
 Ever smoker 1.68 (0.52-5.38) 0.92 (0.27-3.12)
 Current smoker 2.26 (1.58-3.23) 1.27 (0.75-2.15)
Alcohol b
 Nondrinker 1 1
 Light drinker 0.69 (0.17-2.82) 0.42 (0.10-1.74)
 Drinker 2.12 (1.44-3.12) 1.20 (0.76-1.89)

BMI, body mass index; CI, confidence interval; OR, odds ratio.

a

Adjusted for educational level (illiterate/primary school, middle school, and college/university), marital status (married, unmarried, divorced, and widowed), and personal history of diabetes (yes/no).

b

Alcohol drinking was classified as nondrinker, light drinker (<1 time per month for more than 6 months), and drinker (≥1 time per month for more than 6 months).