Skip to main content
. 2021 Oct 8;11:740236. doi: 10.3389/fcimb.2021.740236

Figure 1.

Figure 1

Intervention of GQD decreased blood glucose, and improved oral glucose tolerance and insulin resistance status. (A) Flow diagram of the experimental design. (B) Blood glucose levels over the 12-week experiment. (C) HbA1c levels determined after treatment for 12 weeks. (D) HOMA-IR index was calculated using the following formula: HOMA-IR= FINS × FPG/22.5. (E) Oral glucose tolerance test. (F) AUC calculated from the glucose concentrations versus time for the period of 0-120 min after glucose load by the trapezoidal rule. (G) Serum C-peptide levels determined after treatment for 12 weeks. Values are expressed as means ± SE. Differences were assessed by ANOVA: **p < 0.01, *p < 0.05. HbA1c, glycosylated hemoglobin; HOMA-IR, homeostasis model assessment for insulin resistance; FINS, fasting insulin; FPG, fasting plasma glucose; NC, normal control; DM, diabetes mellitus; GQD, Gegen Qinlian Decoction; Met, metformin.