Table 5.

Differences of patients’ characteristics between the two groups.

Characteristics	Pretreatment LIPI		p-value
	Good	Intermediate/poor
Age (year)
<60	36	12	0.037
≥60	28	24
Sex
Male	53	35	0.051
Female	11	1
Stage
LD	20	6	0.154
ED	44	30
Smoking history
Never smoke	17	4	0.079
Smoke	47	32
ICI drugs
PD-1 inhibitors	41	24	0.83
PD-L1 inhibitors	23	12
ECOG PS
0−1	62	32	0.184
≥2	2	4
Brain metastasis
Yes	13	9	0.621
No	51	27
Liver metastasis
Yes	9	15	0.003
No	55	21
Bone metastasis
Yes	11	18	0.001
No	53	18

ICI, immune checkpoint inhibitor; PD-1, programmed cell death-1; PD-L1, programmed cell death-ligand 1; LD, limited disease; ED, extensive disease; ECOG PS, Eastern Cooperative Oncology Group Performance Status; LIPI, lung immune prognostic index; HR, hazard ratio; CI, confidence interval.