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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Am J Gastroenterol. 2021 Oct 1;116(10):2128–2136. doi: 10.14309/ajg.0000000000001366

Table 6.

Association of phenotypes within RAP+CP patients with severe pain.

Variable Level Controls1 (N=531) Cases2 (N=732) Total (N=818) p-value

Age at Ascertainment Mean (SD) 52 (16.1) 47.1 (15.2) 49.2 (15.8) < 1e-05

Sex Male 265 (49.9%) 377 (51.5%) 642 (50.8%) 0.61
Female 266 (50.1%) 355 (48.5%) 621 (49.2%)

Mental QOL Mean (SD) 46.7 (11) 41.8 (12) 43.7 (11.8) < 1e-05
Missing 90 33 123

Drinking Never 105 (20.0%) 163 (22.3%) 268 (2.3%) 0.36
Ever 421 (80.0%) 569 (77.7%) 990 (78.7%)
Missing 5 0 5

Smoking Never 202 (38.3%) 224 (30.7%) 426 (33.9%) 0.0065
Ever 326 (61.7%) 505 (69.3%) 831 (66.1%)
Missing 3 3 6

EPI No 410 (77.2%) 522 (71.3%) 932 (73.8%) 0.022
Yes 121 (22.8%) 210 (28.7%) 331 (26.2%)

Diabetes No 407 (76.6%) 549 (75.0%) 956 (75.7%) 0.54
Yes 124 (23.4%) 183 (25.0%) 307 (24.3%)

Percentages shown next to the counts are column percentages within each variable.

1

Patients without severe pain.

2

Patients with severe pain.

CP, chronic pancreatitis; RAP, recurrent acute pancreatitis; SD, standard deviation; QOL, quality of life; EPI, exocrine pancreatic insufficiency.