Table 2.
cCD and iCD Stratified by Endoscopic Severity and LILRB3 Expression
| Disease category | LILRB3_Q1 | LILRB3_Q2 | LILRB3_Q2 | LILRB3_Q4 | P value |
|---|---|---|---|---|---|
| Macroscopic inflammation and deep ulcer (iCD) | 1 (1.3%) | 12 (16%) | 22 (29.3%) | 40 (53.3%) | 2.09 × 10-22 |
| Macroscopic inflammation and no deep ulcer (iCD) | 16 (18.8%) | 24 (28.2%) | 31 (36.5%) | 14 (16.4%) | |
| No inflammation and no deep ulcer (cCD) | 10 (41.7%) | 9 (37.5%) | 2(8.3%) | 3 (12.5%) | |
| Undetermined and no deep ulcer (cCD) | 0 (0%) | 0 | 1 (33.3%) | 2 (66.7%) | |
| Microscopic inflammation and deep ulcer (iCD) | 0 | 1 (100%) | 0 | 0 | |
| Microscopic inflammation and no deep ulcer (cCD) | 3 (10.3%) | 12 (41.4%) | 9 (31.0%) | 5 (17.2%) | |
| Non-IBD | 34 (81%) | 7 (16.7%) | 0 | 1 (2.4%) |
NOTE. LILRB3 quartiles were established based on RPKM values: quartiles Q1 (0%–25%), 0.59–1.44; Q2 (26%–50%), 1.48–2.72; Q3 (51%–75%), 2.73–5.47; and Q4 (76%–100%), 5.56–73.39. Statistical analysis was performed using SPSS 17.0. The frequencies procedure was used for the LILRB3 quartile analysis. The χ2 test was used to assess the association of CD categories with 4 LILRB3 quartiles. Value (%) represents the number of patients (% of total of disease category).