Table 1. Characteristics of the Study Population and Myocarditis Cases at Baseline.*.
| Characteristic | Study Population (N=2,558,421) |
Patients with Myocarditis (N=54) |
|---|---|---|
| Median age (IQR) — yr | 44 (30–63) | 27 (21–35) |
| Sex — no. (%) | ||
| Female | 1,309,988 (51) | 3 (6) |
| Male | 1,248,433 (49) | 51 (94) |
| Coexisting illness — no. (%)† | ||
| Any | 9 (17) | |
| Diabetes mellitus | — | 1 (2) |
| Hypertension | — | 7 (13) |
| Dyslipidemia | — | 5 (9) |
| Coronary artery disease | — | 1 (2) |
| Previous pericarditis | — | 1 (2) |
| Known left ventricular dysfunction | — | 1 (2) |
| Medication use — no. (%)† | ||
| Any | 7 (13) | |
| Aspirin | — | 2 (4) |
| P2Y12 inhibitor | — | 1 (2) |
| Beta-blocker | — | 1 (2) |
| ACE inhibitor or ARB | — | 4 (7) |
| Statin | — | 4 (7) |
| Proton-pump inhibitor | — | 1 (2) |
| Insulin | — | 1 (2) |
| Oral hypoglycemic agent | — | 1 (2) |
*
ACE denotes angiotensin-converting enzyme, ARB angiotensin-receptor blocker, and IQR interquartile range.
†
Data regarding coexisting medical conditions and medication use were abstracted from structured fields in notes regarding the patient’s index hospitalization and follow-up. Accordingly, such data were not available for the entire study population. None of the patients had a history of myocarditis.