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. 2021 Feb 6;28(9):997–1008. doi: 10.5551/jat.61267

Table 3. Univariate analysis of factors associated with stroke recurrences.

CAA-related ICH ( n = 60) HTN-related ICH ( n = 103)
HR (95% CI) P value HR (95% CI) P value
Baseline clinical characteristics
Age 0.964 (0.893-1.041) 0.352 1.032 (0.985-1.081) 0.186
Male 2.073 (0.495-8.677) 0.318 1.226 (0.401-3.748) 0.721
Hypertension 0.577 (0.138-2.413) 0.451 / /
Diabetes mellitus 1.861 (0.375-9.227) 0.447 0.632 (0.174-2.298) 0.486
Dyslipidemia 1.223 (0.142-7.537) 0.637 0.728 (0.331-1.601) 0.429
Previous stroke 0.494 (0.061-4.016) 0.510 1.700 (0.377-7.678) 0.490
Antiplatelet use 0.756 (0.222-4.078) 0.529 0.576 (0.067-5.387) 0.689
Statin use 1.275 (0.653-4.338) 0.264 0.835 (0.321-3.965) 0.189
Admission NIHSS 1.116 (0.960-1.297) 0.153 1.124 (0.986-1.280) 0.081
Admission GCS 0.749 (0.223-2.519) 0.641 0.728 (0.331-1.601) 0.429
Hematoma volume 1.033 (1.001-1.066) 0.045 1.012 (0.950-1.079) 0.710
Imaging markers of CVSD
Lacunes 2.120 (0.428-10.510) 0.357 6.132 (2.054-18.311) 0.001
CMBs 1.108 (0.892-1.376) 0.354 0.797 (0.258-2.455) 0.692
EPVS 0.771 (0.184-3.227) 0.722 1.957 (0.658-5.825) 0.228
WMH 1.376 (0.936-2.024) 0.105 1.251 (0.965-1.622) 0.091
cSS 1.979 (0.941-4.160) 0.072 2.176 (0.747-6.343) 0.154
The original SVD score 2.449 (1.076-5.575) 0.033 1.911 (1.193-3.061) 0.007
The modified SVD score 1.904 (1.051-3.448) 0.034 1.586 (1.047-2.403) 0.030
The refined SVD score / / 1.589 (1.007-2.507) 0.047
The CAA-SVD score 1.894 (1.216-2.950) 0.005 / /
Total number of SVD markers 3.839 (1.505-9.794) 0.005 2.136 (1.218-3.745) 0.008

Abbreviation: HTN = Hypertension; CAA = Cerebral Amyloid Angiopathy; ICH = Intracerebral Hemorrhage; NIHSS = National Institutes of Health Stroke Scale; GCS = Glasgow Coma Scale; cSS = Cortical Superficial Siderosis; CMBs = Cerebral Microbleeds; WMHs = White Matter Hyperintensities; EPVSs = Enlarged Perivascular Spaces; CSO = Centrum Semiovale ; BG = Basal Ganglia; SVD = Small Vessel Disease.