Table 4. Multivariable adjusted models exploring associations of individual SVD markers and different SVD scores and functional dependence ^＊ in CAA-related ICH patients .

	OR (95% CI)	P value
Model 1: individual SVD markers
Age	1.098 (0.983-1.226)	0.097
Admission NIHSS	1.211 (0.967-1.516)	0.095
Hematoma volume	0.985 (0.903-1.075)	0.735
Lacunes	0.349 (0.023-5.400)	0.451
Lobar CMBs	2.486 (0.360-17.156)	0.355
Severe CSO-EPVS	4.778 (0.568-400.125)	0.150
WMH	2.881 (0.234-35.407)	0.408
cSS	4.665 (1.388-15.679)	0.013
Model 2: different total SVD scores
Age	1.120 (1.014-1.237)	0.026
Admission NIHSS	1.249 (0.979-1.594)	0.074
Hematoma volume	1.023 (0.935-1.120)	0.617
The original SVD score	0.129 (0.010-1.640)	0.114
The modified SVD score	3.816 (0.321-45.355)	0.289
The refined SVD score	0.802 (0.095-6.764)	0.839
The CAA-SVD score	3.429 (1.518-7.748)	0.003
Total number of SVD markers	1.410 (0.180-11.030)	0.744

Abbreviation: SVD = Small Vessel Disease; CAA = Cerebral amyloid angiopathy; NIHSS = National Institutes of Health Stroke Scale; cSS = Cortical Superficial Siderosis; CMBs = Cerebral Microbleeds; WMH = White Matter Hyperintensities; EPVS = Enlarged Perivascular Spaces; CSO = Centrum Semiovale.

^＊ Functional dependence was measured 3 months after onset and defined as the modified Rankin scale (mRS) ＞2