Table 6. Multivariable adjusted models exploring associations of individual SVD markers and different total SVD scores and stroke recurrences in CAA-related ICH patients.
| HR (95% CI) | P value | |
|---|---|---|
| Model 1: individual SVD markers | ||
| Age | 0.948 (0.868-1.036) | 0.241 |
| Hematoma volume | 1.022 (0.983-1.062) | 0.266 |
| Lacunes | 2.211 (0.257-19.055) | 0.470 |
| Lobar CMBs | 1.013 (0.177-5.804) | 0.988 |
| Severe CSO-EPVS | 1.596 (0.348-7.328) | 0.548 |
| WMH | 1.376 (0.936-2.024) | 0.105 |
| cSS | 1.953 (0.929-4.107) | 0.078 |
| Model 2: different total SVD scores | ||
| Age | 0.945 (0.874-1.020) | 0.148 |
| Hematoma volume | 1.020 (0.977-1.065) | 0.370 |
| The original SVD score | 1.107 (0.094-12.998) | 0.935 |
| The modified SVD score | 0.549 (0.049-6.218) | 0.629 |
| The refined SVD score | 3.468 (0.447-26.881) | 0.234 |
| The CAA-SVD score | 1.304 (0.548-3.101) | 0.549 |
| Total number of SVD markers | 3.765 (1.467-9.663) | 0.006 |
Abbreviation: SVD = Small Vessel Disease; CAA = Cerebral amyloid angiopathy; cSS = Cortical Superficial Siderosis; CMBs = Cerebral Microbleeds; WMH = White Matter Hyperintensities; EPVS = Enlarged Perivascular Spaces; CSO = Centrum Semiovale.