Table 7. Multivariable adjusted models exploring associations of individual SVD markers and different total SVD scores and stroke recurrences in HTN-related ICH patients.
| HR (95% CI) | P value | |
|---|---|---|
| Model 1: individual SVD markers | ||
| Age | 1.032 (0.985-1.081) | 0.186 |
| Admission NIHSS | 1.108 (0.954-1.288) | 0.179 |
| Lacunes | 5.064 (1.697-15.116) | 0.004 |
| Deep CMBs | 0.572 (0.150-2.174) | 0.412 |
| Severe BG-EPVS | 0.275 (0.020-3.857) | 0.338 |
| WMH | 1.330 (0.606-2.916) | 0.477 |
| cSS | 3.135 (0.799-12.309) | 0.101 |
| Model 2: different total SVD scores | ||
| Age | 1.035 (0.980-1.093) | 0.212 |
| Admission NIHSS | 1.111 (0.968-1.276) | 0.135 |
| The original SVD score | 1.833 (0.702-4.784) | 0.216 |
| The modified SVD score | 0.575 (0.119-2.792) | 0.493 |
| The refined SVD score | 1.056 (0.264-4.232) | 0.939 |
| The CAA-SVD score | 1.582 (0.614-4.074) | 0.342 |
| Total number of SVD markers | 2.136 (1.218-3.745) | 0.008 |
Abbreviation: SVD = Small Vessel Disease; HTN = Hypertension; NIHSS = National Institutes of Health Stroke Scale; cSS = Cortical Superficial Siderosis; CMBs = Cerebral Microbleeds; WMH = White Matter Hyperintensities; EPVS = Enlarged Perivascular Spaces; BG = Basal Ganglia.