Table 3.
SNP | Chr:BP | Genes | EA | NEA | EAFR | β | se | P |
---|---|---|---|---|---|---|---|---|
rs3101341 | 1:72747844 | NEGR1 | T | C | 0⋅800 | −0⋅068 | 0⋅183 | 0⋅709 |
rs66495454 | 1:72748567 | NEGR1 | GTCCT | G | 0⋅234 | 0⋅240 | 0⋅177 | 0⋅174 |
rs506589 | 1:177894287 | SEC16B | C | T | 0⋅270 | 0⋅030 | 0⋅165 | 0⋅856 |
rs36016753 | 1:187269477 | - | A | G | 0⋅185 | 0⋅243 | 0⋅189 | 0⋅198 |
rs10900457 | 1:205146726 | CNTN2, RBBP5, etc. | A | G | 0⋅461 | 0⋅144 | 0⋅148 | 0⋅330 |
rs62106258 | 2:417167 | - | NA | NA | NA | NA | NA | NA |
rs6786550 | 3:62560523 | CADPS | C | T | 0⋅680 | 0⋅085 | 0⋅156 | 0⋅586 |
rs7644667 | 3:69040601 | EOGT, TMF1, etc. | C | T | 0⋅064 | 0⋅386 | 0⋅299 | 0⋅196 |
rs13340130 | 3:81790970 | GBE1 | T | A | 0⋅528 | −0⋅002 | 0⋅146 | 0⋅990 |
rs701760 | 4:113439212 | NEUROG2, LARP7 | G | C | 0⋅320 | 0⋅371 | 0⋅157 | 0⋅018 |
rs300046 | 5:37081705 | NIPBL, C5orf42, etc. | G | A | 0⋅500 | −0⋅163 | 0⋅152 | 0⋅282 |
rs10064431 | 5:92950673 | FAM172A | C | T | 0⋅614 | 0⋅273 | 0⋅150 | 0⋅068 |
rs9379831 | 6:26175852 | HIST1H2AC, HIST1H1E, etc. | A | C | 0⋅165 | −0⋅051 | 0⋅235 | 0⋅829 |
rs806794 | 6:26200677 | HIST1H2AC, HIST1H1E, etc. | G | A | 0⋅839 | −0⋅078 | 0⋅238 | 0⋅744 |
rs35797675 | 7:72878044 | FZD9, BAZ1B, etc. | G | T | 0⋅108 | −0⋅490 | 0⋅240 | 0⋅041 |
rs4034907 | 7:135050259 | CNOT4, NUP205 | GATAA | G | 0⋅759 | 0⋅128 | 0⋅173 | 0⋅459 |
rs10125463 | 9:15677925 | CCDC171 | T | A | 0⋅223 | 0⋅074 | 0⋅175 | 0⋅674 |
rs6478868 | 9:131927092 | FAM73B, DOLPP1, etc. | C | T | 0⋅106 | −0⋅034 | 0⋅237 | 0⋅885 |
rs1912286 | 10:87318888 | - | A | G | 0⋅493 | 0⋅074 | 0⋅147 | 0⋅614 |
rs3909727 | 11:126587382 | KIRREL3 | NA | NA | NA | NA | NA | NA |
rs4759074 | 12:54664097 | CBX5, HNRNPA1, etc. | T | C | 0⋅632 | 0⋅312 | 0⋅150 | 0⋅038 |
rs12103229 | 16:74167594 | - | A | C | 0⋅360 | −0⋅117 | 0⋅152 | 0⋅443 |
rs12232804 | 19:42677807 | ATP1A3, GRIK5, etc. | T | C | 0⋅054 | 0⋅599 | 0⋅326 | 0⋅066 |
rs429358 | 19:45411941 | PVRL2, TOMM40, etc. | C | T | 0⋅101 | 0⋅392 | 0⋅244 | 0⋅109 |
rs838144 | 19:49250239 | FUT2, MAMSTR, etc. | T | C | 0⋅980 | −0⋅097 | 0⋅642 | 0⋅880 |
rs79564737 | 20:43408372 | RIMS4 | A | G | 0⋅535 | −0⋅100 | 0⋅146 | 0⋅494 |
rs136528 | 22:27245262 | - | C | G | 0⋅634 | 0⋅105 | 0⋅152 | 0⋅491 |
rs139911 | 22:40704052 | TNRC6B | T | C | 0⋅461 | −0⋅249 | 0⋅146 | 0⋅087 |
rs202637 | 22:41853928 | ZC3H7B, TEF, etc. | G | A | 0⋅954 | 0⋅312 | 0⋅349 | 0⋅371 |
SNP, single nucleotide polymorphism; Chr, chromosome, chromosomal position (GRCh37/hg19); EA, effect allele; NEA, non-effect allele; EAF, effect allele frequency; β, effect size; se, standard error of effect size. NA, not available in the J-MICC data – indicates no genes hit on that SNP.
We carried out a replication study on the twenty-nine identified SNPs associated with meat intake of European participants in the study by Niarchou et al.(18).