Table 1. X-linked TLR7 deleterious variants in 16 unrelated male patients with life-threatening COVID-19 pneumonia.
| Patient | Genotype | Age [years] | Ethnicity | Ancestry/residence | Outcome |
| P1 | L134P/Y | 45 | Admixed American | Paraguay/Spain | Survived |
| P2 | N158Tfs11*/Y | 60 | European | France | Deceased |
| P3 | L227fs*/Y | 34 | Middle East | Iran | Survived |
| P4 | D244Y/Y | 13 | Middle East | Turkey | Survived |
| P5 | F310L/Y | 39 | Middle East | Iran | Survived |
| P6 | L372M | 7 | Caucasian (Central Asia based on GME Variome) | Iran | Survived |
| P7 | I505T/Y | 55 | European | Italy | Survived |
| P8 | H630Y/Y | 50 | European | Spain | Survived |
| P9 | I657T/Y | 18 | European | Italy | Survived |
| P10 | F670Lfs*8 | 31 | European | Sweden | Survived |
| P11* | F670Lfs*8 | 29 | European | Sweden | Survived |
| P12 | K684*/Y | 30 | European | Spain | Survived |
| P13 | P715S/Y | 40 | Latino | Colombia | Survived |
| P14 | H781L/Y | 13 | Middle East | Russia/France | Survived |
| P15 | L988S/Y | 26 | Middle East | Iran | Deceased |
| P16 | L988S/Y | 20 | Middle East | Turkey | Survived |
| P17 | M854I;L988S/Y | 71 | European | Italy | Survived |
* P10’s brother (not included in the cohort of 1,202 critical patients with critical COVID-19 pneumonia).
GME Variome, Greater Middle Eastern Variome Project