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. Author manuscript; available in PMC: 2021 Oct 22.
Published in final edited form as: Int J Toxicol. 2021 Jul 19;40(5):442–452. doi: 10.1177/10915818211031239

Table 5:

Coagulation results

Group Treatment Gender PT (sec) FIB (mg/dL)
Day 31 Day 43 Day 31 Day 43
1 0.9% Saline (control) M 15.77 15.55 377.1 367.0
2 0.5 mg CPG 7909 M 16.55* 15.91 528.4* 366.3
3 AV7909 Lot 1 M 16.97* 16.05 858.7* 356.3
4 AV7909 Lot 2 M 17.22* 16.45* 798.9* 409.2
1 0.9% Saline (control) F 15.30 15.30 284.7 279.9
2 0.5 mg CPG 7909 F 15.21 15.57 378.4* 253.0
3 AV7909 Lot 1 F 16.44* 15.77* 749.6* 248.1
4 AV7909 Lot 2 F 16.66* 16.10* 605.2* 255.7

M - male; F - female; PT – prothrombin time; FIB – Fibrinogen

*

- Significantly different from the control value, p < 0.05