TABLE 5.
Serological follow-up of five transplant recipients
Patient and age (yr) | Clinical status (mo/yr)a | Date of serum collection (day/mo/yr) | IF titer of antibody
|
Immunoblot titer of antibodyb
|
Interpretationsc
|
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IgG
|
IgM
|
||||||||||||||
VCA IgG | VCA IgM | EBNA IgG | VCA p23 | EA
|
EBNA p72 | VCA p23 | EA
|
EBNA p72 | IF | Immunoblot | |||||
p54 | p138 | p54 | p138 | ||||||||||||
1 (36) | Kidney transplant (03/92) | 16/4/92 | <5 | <10 | <5 | − | − | − | − | − | + | + | − | SN | SN |
31/8/92 | 640 | ≥10 | <5 | − | + | + | − | − | ++ | + | − | PI | PI | ||
22/1/93 | 2,560 | 10 | <5 | + | + | + | − | − | + | + | − | R* | PI | ||
9/10/95 | 5,120 | <10 | <5 | ++ | + | + | − | − | + | + | − | R* | PI | ||
25/11/96 | 5,120 | <10 | <5 | ++ | + | + | − | − | + | + | − | R* | PI | ||
2 (61) | Heart transplant (01/91) | 6/7/94 | 5,120 | 10 | 40 | +++ | +++ | + | + | + | + | + | − | R | R |
17/3/95 | 5,120 | 10 | 20 | +++ | +++ | + | + | + | + | + | − | R | R | ||
11/10/95 | 5,120 | 10 | 40 | +++ | +++ | + | + | + | + | + | − | R | R | ||
23/10/96 | 5,120 | 10 | 40 | +++ | +++ | + | + | + | + | + | − | R | R | ||
3 (13) | Heart transplant (85) | 14/12/94 | 2,560 | <10 | 5 | +++ | + | + | − | − | − | − | − | R | R |
15/3/95 | 5,120 | <10 | 5 | +++ | + | + | − | − | − | − | − | R | R | ||
17/4/96 | 5,120 | <10 | 5 | +++ | + | + | − | − | + | − | − | R | R | ||
18/10/96 | 5,120 | <10 | 5 | +++ | + | + | − | − | + | − | − | R | R | ||
4 (29 mo) | Kidney and heart transplant (08/96) | 11/9/96 | <5 | <10 | <5 | − | − | − | − | − | − | + | − | SN | SN |
9/10/96 | <5 | <10 | <5 | − | − | − | − | − | − | + | − | SN | SN | ||
10/12/96 | 80 | 10 | <5 | − | − | − | − | − | − | + | − | PI | SN | ||
20/12/96 | 80 | 10 | <5 | − | − | − | − | − | − | + | − | PI | SN | ||
3/1/97 | 1,280 | 10 | <5 | − | + | − | − | − | − | + | − | PI | PI | ||
17/1/97 | 1,280 | 10 | <5 | − | + | − | − | − | + | + | − | PI | PI | ||
4/2/97 | 1,280 | 10 | <5 | + | + | + | − | − | + | + | − | PI* | PI | ||
5 (49) | Kidney transplant (94) | 8/3/95 | ≥5,120 | <10 | 20 | +++ | ++ | + | + | + | − | − | − | R | R |
25/4/96 | ≥5,120 | <10 | 40 | +++ | ++ | + | + | + | − | − | − | R | R | ||
26/11/96 | ≥5,120 | <10 | 40 | +++ | ++ | + | + | + | − | − | − | R | R |
If month is unknown, year only is given in parentheses.
The number of plus (+) signs corresponds to band intensity.
SN, seronegative; PI, primary infection; R, reactivation; *, possible chronic infection. Boldface designations denote discrepancies between the IF and immunoblot interpretations.