Table 1.
Multivariate Cox regression analysis of influence of factors on survival in bulbar onset ALS patients
| Variable | HR | 95% CI | P |
|---|---|---|---|
| Gender | |||
| Famale | 1.000 | ||
| Male | 0.721 | 0.470–1.106 | 0.134 |
| Onset age (year) | 1.018 | 0.998–1.038 | 0.074 |
| Duration (month) | 0.912 | 0.886–0.939 | < 0.001 |
| ALSFRS-R | 0.986 | 0.955–1.018 | 0.380 |
| Use of riluzole | |||
| No | 1.000 | ||
| Yes | 1.170 | 0.755–1.812 | 0.483 |
| Use of NIV | |||
| No | 1.000 | ||
| Yes | 0.951 | 0.577–1.568 | 0.844 |
ALS amyotrophic lateral sclerosis, Duration duration from bulbar onset to first significant limb involvement, ALSFRS-R Revised ALS Functional Rating Scale, NIV noninvasive ventilation