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. 2021 Oct 22;1(4):100048. doi: 10.1016/j.jcvp.2021.100048

Table 3.

Predictors of COVID-19 severity and mortality. Abbreviations; CVD, Cardiovascular diseases; GGO, Ground glass opacities; 95% CI, 95 percent confidence interval.

Univariate analysis Multivariate logistic regression
Odds ratio 95% CI P value Odds ratio 95% CI p-value
Endpoint: COVID-19 Severity
Male sex 1.76 1.26 to 2.46 0.0008
Age > 60 years 2.12 1.51 to 2.97 < 0.0001
Blood type O 1.66 1.01 to 2.74 0.04
Immunosuppression before COVID-19 0.4 0.22 to 0.72 0.0019 0.183 0.05 to 0.67 0.011
≥ 2 Comorbid conditions 1.52 1.07 to 2.15 0.017
0 Comorbid conditions 0.6 0.43 to 0.83 0.0026
CVD 1.99 1.30 to 3.04 0.0012
Diabetes 1.48 1.01 to 2.16 0.038
Endpoint: COVID-19 related death
Age >60 years 3.4 2.31 to 5.01 < 0.0001 1.05 1.03 to 1.07 < 0.0001
≥ 2 Comorbid conditions 3.27 2.29 to 4.66 < 0.0001
Bilateral GGOs 3.34 0.87 to 12.76 0.038
Consolidations 2.3 1.76 to 3.01 < 0.0001 12 2.63 to 55.08 0.0013
Ferritin ≥ 4000 ng/mL 9.29 4.42 to 19.52 < 0.0001 1 1 to 1 < 0.0001
Procalcitonin ≥ 1.5 ng/mL 9.45 5.32 to 16.81 < 0.0001
D-Dimer ≥ 5000 ng/mL 7.55 4.10 to 13.90 < 0.0001 1 1 to 1 < 0.0001