Table 2.
Minimal inhibitory concentrations (MICs) (mg/L) of antifungal agents alone or combined with FK520.
| Isolates | POS 1 | FLC | ITC | VRC | CAS | MCF | ANF | AMB | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| − | + | − | + | − | + | − | + | − | + | − | + | − | + | − | |
| ATCC2001 | 0.25 | 0.03 | 2 | 1 | 0.25 | 0.03 | 0.06 | 0.03 | 0.25 | 0.03 | 0.06 | 0.03 | 0.06 | 0.03 | 1 |
| BMU10720 | 4 | 0.12 | 4 | 2 | 2 | 0.06 | 0.12 | 0.06 | 32 | 8 | 8 | 4 | 4 | 2 | 1 |
| BMU10722 | 4 | 0.12 | 4 | 2 | 2 | 0.06 | 0.12 | 0.06 | 32 | 8 | 8 | 4 | 4 | 2 | 1 |
1 POS, posaconazole; FLC, fluconazole; ITC, itraconazole; VRC, voriconazole; CAS, caspofungin; MCF, micafungin; ANF, anidulafungin; AMB, amphotericin B; (−): in the absence of FK520; (+): in the presence of 100 mg/L FK520.