Table 2.

Paired t-test comparing the blood biomarkers before and after treatment

Parameter	Control group, mean±SD	P	Study group, mean±SD	P
TNF-α
Before treatment	278.20±11.37	<0.001*	281.30±11.79	<0.001*
After treatment	178.20±5.69		135.35±6.46
IL-1
Before treatment	1.63±0.04	<0.001*	1.65±0.06	<0.001*
After treatment	0.79±0.70		0.36±0.02
IL-6
Before treatment	156.66±33.11	<0.001*	170.25±2.88	<0.001*
After treatment	106.44±22.07		63.75±0.96